Cemento-ossifying fibroma is classified as an osteogenic tumor, defined as a well -differentiated tumor, occasionally encapsulated, comprising fibrous tissue. Abstract. Introduction: Cemento-ossifying fibroma is a benign fibro-osseous maxillary tumor belonging to the same category as fibrous dysplasia and. Background: Cemento-Ossifying Fibroma (COF) is considered by most as relatively rare, benign, non-odontogenic neoplasm of the jaw bones and other.

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CT of calcifying jaw bone diseases. Cemento-ossifying fibromas COFs are benign lesions affecting demento jaws and other craniofacial bones. The reasons for considering periodontal ligament origin for peripheral ossifying fibroma include exclusive occurrence of peripheral ossifying fibroma in the gingiva interdental papillathe proximity of gingiva to the periodontal ligament, and the presence of oxytalan fibres within the mineralized matrix of some lesions [ 10 ].

However, Eversole and his co-workers in a study of 64 cases of cemento-ossifying fibroma reported a recurrence rate of as high as 28 per cent following surgical curettage of these lesions. Occasionally bleeding occurred when he brushed his teeth.

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An attempt has been made by Endo et al. View at Google Scholar J.

Endo et al attempted to distinguish COF from ossifying fibroma and fibrous dysplasias by immunohistochemistry. You can also scroll through stacks with your mouse wheel or the keyboard arrow keys.

Cemento-ossifying fibroma

Int J Oral Maxillofac Surg. No history of previous similar swelling, toothache, or numbness could be elicited. The following case report attempts to fibrroma between lesions presenting with similar clinical, radiographic and histologic presentations; as well as describe the varying manifestations of COF, with reference to previous literature.


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Cemento-Ossifying Fibroma- A Case Report

J Oral Maxillofac Surg. Best cases from the AFIP: The World Fibrpma Organization histological typing of odontogenic tumours: The well-defined border of the central cementoossifying fibroma helps differentiate it from the aggressive sarcomas and carcinomas. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.

Fibro-osseous lesions of the jaws have been classified by Waldron and Kramer et al.

The concept of fibroosseous lesions of bone has evolved over the last several decades and now includes two major entities: Peripheral cemento-ossifying fibroma is a relatively rare tumour classified between fibroosseous lesions.

Various lesions may show clinical and radiographic resemblance to COF as mentioned above. Case Report A 35 year old female patient reported with a complaint of swelling on the lower left jaw since past 2 months [ Figure 1 ]. Histopathological picture showing tightly cellular connective tissue stroma with abundant hyperchromatic fibroblasts and sparely collagen fibres along with scattered irregular shaped basophilic cementum like tissue. Cemento-ossifying fibroma of the petromastoid region: Clinical, radiographic and histopathologic features of COF and other fibro-osseous lesions are overlapping and may cause confusion fibromaa classification, diagnosis and treatment.

Cemento-ossifying fibroma | Radiology Reference Article |

Thus, this points to trauma as a possible triggering factor, postulating the lesion to be fibbroma connective tissue reaction rather than a genuine neoplasm. Lateral oblique radiograph showing a well defined radiolucency of the approximate size of 6.


Despite a cemenyo of the literature supporting differentiation, some authors continue to argue that the POF or peripheral cemento-ossifying fibroma is the peripheral counterpart of the central cemento-ossifying fibroma [ 21 ]. Occlusal radiograph showed well-defined expansion of both the buccal and lingual cortical plates arising from lower right first molar region, cemneto evidence of ill-defined diffuse septa, suggesting a multi-locular appearance with diffuse irregular radiopacity within the largely radiolucent lesion Figure 3.

Root resorption of lower right first and second molars was evident. The POF lesion is generally small and does not require imaging beyond radiographs [ 18 ].

It commonly presents as a progressively growing lesion that can attain an enormous size with resultant deformity if left untreated. To view the erratum, please click here.

The following features were observed during microscopic examination: The surface of the occlusal plane was pinkish red in color Figure 1. An incisional biopsy was performed, histological examination revealed as tightly cellular connective tissue stroma with abundant spindle shaped hyperchromatic fibroblasts and sparely flbroma fibres along with scattered numerous irregular shaped basophilic cementum like tissue.

They are usually small but can become large.

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