Dysbaric osteonecrosis (DON) is the destruction of bone tissue in the long bones, hips and shoulders associated with diving and compressed-air work. Dysbaric osteonecrosis is a term used to describe aseptic or avascular bone necrosis due to ischemia caused by gas bubbles, although the exact mechanism is. Dysbaric osteonecrosis (DON) was first identified in the s and was found to be relatively common in the s and early s in some.

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Dysbaric osteonecrosis – Wikipedia

Fifty-six male divers, who were engaged in shellfish collection or structural work in Ohura, Saga Prefecture, Japan, received radiographic skeletal examinations for DON after giving informed consent. For Permissions, please email: Compared to technical divers, the number of cases among recreational divers is much smaller, but some cases are reported. Other causes of osteonecrosis: StatPearls Publishing; Jan.

Recommendations for the management of secondary hypogammaglobulinaemia due to B cell targeted therapies in autoimmune rheumatic diseases. Clin Orthop Relat Res.

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Dysbaric osteonecrosis: a reassessment and hypothesis.

RheumatologyVolume 45, Issue 7, 1 JulyPages —, https: The prevailing view is that recreational divers are at lower risk than commercial divers and compressed-air workers since they are supposed to perform dives with conservative exposures. MRI of osteonecrosis in the hips. In Konig described necrosis dysbaricc the adult femoral head without infection 3 aseptic necrosis of bone and in the same year Twynam reported a case of osteonecrosis in a caisson worker 4 in which there was dywbaric a significant infective component.


Limited studies have shown that DON is not a significant risk for recreational divers. Edaravone, a novel free radical scavenger, prevents steroid-induced osteonecrosis in rabbits.

There is no specific staging system for dysbaric osteonecrosis itself. The multivariate logistic regression analysis showed that PAI-1 levels greater than Definition of bone necrosis by the pathologist.

Divers risk DON with significant inert gas loading followed by inadequate decompression.

Technical diving is theoretically regarded as a risky practice since divers are exposed to prolonged ongassing using heliox or trimix, which implies specific but often empirical decompression procedures.

This is also consistent with the fact that the incidence of avascular necrosis from all causes is more common in men as well. Lifestyle and dietary measures along with predive and postdive hydration may reduce the deleterious effects of venous stasis slow blood flow in the medullary cavities of bones following decompression. The ratio of apoB to apoA1 was calculated.

Transitional changes in the incidence of osteonecrosis in systemic lupus erythematosus patients: Osteknecrosis risk increased with greater deviations from safe decompression procedures. Bond Robert Boyle Albert A.


Histopathology Histologic evidence of empty osteocytic lacunae is consistent with osteonecrosis. Dysbaric osteonecrosis DON is a complication of ineffective decompression following exposure to high-pressure environments. The lesion begins as a localised area of infarctionusually without symptoms.

Alert Diver | Dysbaric Osteonecrosis in Recreational Diving

Recognized risk factors for osteonecrosis include chronic steroid use, coagulopathies, alcoholism, smoking, antiretroviral drugs and many other conditions. Our preliminary data showed that the PAI-1 level of five healthy volunteers four osteoonecrosis and a woman, age Sharareh B, Schwarzkopf R.

Diaphyseal damages are painless. This study has shown the presence of coagulation abnormality in divers with DON.

Citing articles via Web of Science This result suggests that a pharmacological approach incorporating the use of an anticoagulant may represent a potential strategy for the prevention of DON. Ohta Y, Matsunaga H. An important limitation of this study is that only divers were examined and that healthy controls were not. Subchondral fractures may be evident. Clear Turn Off Turn On.

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