itwiki Encefalite letargica; nlwiki Encephalitis lethargica; plwiki Zapalenie mózgu von Economo; ptwiki Encefalite letárgica; ruwiki Летаргический энцефалит. Date, Source, von Economo C. Die Encephalitis lethargica (Mit zwölf lithographischen Tafeln). Franz Deuticke, ss. Leipzig-Wien. Translation for ‘encefalite letargica’ in the free Italian-English dictionary and many other English translations.
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American Medical Association; Chicago: Bull Off intHyg publ.
Zur Klinik der Encephalitis epidemica, unter besonderer Berucksichtigung der Prognose und des Blutbildes. Infectious diseases — viral systemic diseases A80—B34— Others isolated a variety of cocci, but could not be certain that their presence was not the result of secondary infection Ribbert ; Parsons This cannot be attributed to poor record-keeping, as investigators diligently sought cases in non-Western countries in the hope that they might illuminate the EL problem.
The disease attacks the brain, leaving some victims in a statue-like condition, speechless and motionless. Constantin von Economo Substantia nigra. It was the chronic EL symptoms which set the disorder apart not only from influenza but also from other alternatives: Bernard L, Renault J.
Influenza encephalitis is, in any case, now quite rare; otherwise one can orient oneself diagnostically according to the two poles: Even today, influenza virus and genetic material can only rarely be isolated from cerebrospinal fluid CSF or autopsied brain material incases of presumed influenza CNS infection Johnsonpp f. Leyden E, Guttmann S. Although isolated cases of parkinsonism attributed to influenza have been described since the s pandemic, and despite the fact that the influenza A virus exhibits a certain tropism for the substantia nigra in laboratory animals Mattock et al ; Takahashi et al ; Yamada et al ; Casals et al ; Mihara et al ; Takahashi and YamadaEL-like symptoms have not been associated to any degree with influenza.
The reporting of such symptoms might also occur in response to prompting from the physician, as in this EL case:.
Encephalitis lethargica – Wikipedia
He specifically noted that encephalitis grippalis often attacked the cerebral motor zone, and that there had been no confirmed cases in which:. Lethargic encephalitis encefalihe Karachi during an epidemic of influenza. Ergebn Inn Med Kinderheilk.
Somnolence was initially regarded as the primary symptom of EL, but extreme sleepiness could also accompany influenza. Even transplacental transmission encefalitr more the exception than the rule, and the few cases reported impressed some observers as evidence for the specificity of the EL virus Jorge Das Blutbild bei 65 Kranken mit Parkinsonismus post Encephalitis lethargica. The impression which emerges from this debate is that the individual features identified by the skeptics were not absolutely pathognomic for EL, but, on the other hand, their combination in one disorder had not previously been described for any other disease.
Virchows Arch Pathol Anat Physiol. This contrasted sharply with typical depictions of EL sleep: The somnolence persisted for a period of hours to weeks, and could be associated with cataleptic or catatonic symptoms. You must also include a United States public domain tag to indicate why this work is in letaggica public domain in the United States.
But he also noted that: Despite intensive investigations throughout the s, the etiology of the disorder was never conclusively determined. Observations on a green producing coccus from the brain in a case of encephalitis.
The only conclusion we would like to provisionally derive from the descriptions by Stern and von Economo is that the deeper airways are infested in the initial stage of influenza encephalitis to a greater degree, while the infection of the respiratory tract in encephalitis lethargica is restricted to pharyngitis. The published medical literature was limited to a few cases; official circles dismissed it entirely. Proc Roy Soc Med London ; Nearly five million people were affected, a third of whom died in the acute stages.
The specific problem is: Ravenholt and William H.
The patient, whilst completely unconscious of his surroundings with total absence of any suffering, would move restlessly from side to side with his head thrown back and mouth partly opened. The preferred age of onset by EL did not vary significantly throughout the s, with those aged 12 to 35 years most at risk. Further reports and papers on epidemic influenza, —92; with introduction by Medical Officer of Local Government Board.
Some who shared his view nevertheless suspected that EL and influenza might be somehow related, just as measles and whooping cough were then regarded as allied disorders as they often occurred together in a population.
Am J Med Sci.