Common Name: West African Rubber Tree. Funtumia elastica. Drawing of the leaves and flowers. Photograph by: Matilda Smith Public domain. Funtumia elastica (Preuss) Stapf [family APOCYNACEAE]. Common names. English West African rubber tree; Lagos silk rubber tree; bush rubber (Ghana. Description. Tree to 30 m tall; bole straight and cylindrical, crown narrow; bark brown to dark, thin, slightly fissured, becoming granular on old trees; Slash orange.

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Antimicrobial and anti-inflammatory properties of Funtumia elastica.

A colorimetric method for the determination of sugars. Based on these and related studies, novel therapeutic protocols that focus on increasing the functional activity of this T cell population are being pursued in the clinic to combat infection and cancers [ 21 — 23 ].

Suppression of allergic reaction by lambda-carrageenan: The only published characterizations of Funtumia elastica describes the isolation of steroidal alkaloids from its leaves and bark with antiplasmodial [ 52 ] or antifungal activity [ 53 ]. Antigens in tea-beverage prime human Vgamma 2Vdelta 2 T cells in vitro and in vivo for memory and nonmemory antibacterial cytokine responses. Recognition profile of Morus nigra agglutinin Morniga G expressed by monomeric ligands, simple clusters and mammalian polyvalent glycotopes.

The average was based on expression in treated cells from 3 different calves and compared to their expression after uLPS middle and PBS left treatment.

Funtumia elastica

Three separate experiments are shown, thin bar indicates mean, thick error bars represent SEM. GraffEmily M. Animal models of asthma. In Africa some parts of the tree are also used medicinally: Treatment of infectious diseases with immunostimulatory oligodeoxynucleotides containing CpG motifs.

Requirement for gamma delta T cells in allergic airway inflammation. Electrophoretic analysis of heterogeneous lipopolysaccharides from various strains of Vibrio vulnificus biotypes 1 and 2 by silver staining and immunoblotting. Am J Respir Cell Mol. The funtmuia succinimidyl ester CFSE assay for human cells has been recently described [ 1 elasticaa.


The majority of in vitro macrophage activation exhibited by extracts of some immune enhancing botanicals is due to bacterial lipoproteins and lipopolysaccharides.

These fractions were analyzed by HPLC, funtumai elution was monitored with a refractive index detector as described previously [ 30 ]. Thin bar indicates mean, thick error bars represent SEM. Originating in tropical Africa; it has been introduced and cultivated pantropically, including South-East Asia. The floss of the fruits is used like kapok, to stuff cushions. The supernatant fluid was removed and the process was repeated with fresh Polymyxin Support beads.

Professional antigen-presentation function by human gamma delta T Cells. The seed has been used to adulterate Strophanthus seed in the production of strophantin.

Funtumia elastica – Useful Tropical Plants

Briefly, the extracts were mixed with anthrone reagent 0. Flowers in axillary, many-flowered cymes, 5-merous, white to yellowish; peduncle 1 cm long; pedicel mm long; calyx 5 mm long, deeply divided, segments on the inside with 2 glands; corolla salver-shaped, tube mm long, segments oblong, about 5 mm long. Thus, related polysaccharides of various sizes comprise the Yam-I fraction. Hybridization, staining and scans were performed as previously described, and analysis was done using GeneSpring Silicon Genetics with robust multi array RMA preprocessing and Microsoft Excel.

Associated Data Supplementary Materials Variability in elastic vitro macrophage activation by commercially diverse bulk echinacea plant material is predominantly due to bacterial lipoproteins and lipopolysaccharides. It was also apparent that vuntumia with Yam-I at many doses greatly reduced variability between animals; however, fubtumia variation between PBS-treated animals precluded statistical significance within experiments. The relevant fractions were pooled and concentrated.

At present it is economically of no importance. As a service to our customers we are providing this early version of the manuscript. Differential production of interferon-gamma and interleukin-4 in response to Th1- and Th2-stimulating pathogens by gamma delta T cells in vivo.


Eight hours after infection, mice were treated with varying doses of Yam-I by i. Open in a separate window. Tree, up to 30 m tall with not straight, cylindrical, unbuttressed bole; bark pale with grey patches and dark brown twigs, containing white latex. These smaller fractions, elastiva were difficult to generate, were used for limited in vitro assays. Therapeutic treatment with Yam-I resulted in decreased bacterial counts in feces from mice with Salmonella enterica serotype Typhimurium ST -induced enterocolitis.

Antigen recognition elaatica human T cell receptor gamma-positive lymphocytes. Negative regulation of airway responsiveness that elzstica dependent on gamma delta T cells and independent of alphabeta T cells.

Anim Health Res Elaastica. Pretreatment of mice with streptomycin provides a Salmonella enterica serovar Typhimurium colitis model that allows analysis of both pathogen and host.

Funtumia elastica – Wikipedia

Navigation menu Personal tools Log in Request account. After 5 days, the cells were analyzed by two-color flow cytometry. Immunoregulatory rlastica of gamma delta T cells.

Error bars represent SD. Support Center Support Center. These data were derived from single microarrays per treatment with mixed RNA from 3 different calves, which precluded strict interpretation. Down modulation of the inflammatory response to bacterial infection by gamma delta T cells cytotoxic for activated macrophages.

Author information Copyright and License information Disclaimer. The publisher’s final edited version of this article is available at Int Immunopharmacol. Each resulting fraction was applied to bovine PBMC cultures for 24 hours.

The in vivo activity of low concentrations of Yam-I were consistent with the low functional concentrations found in in vitro assays, suggesting that the Yam-I fraction is a concentrated source of the bioactive agonists.

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